Detalles de la búsqueda
1.
Meropenem-ANT3310, a unique ß-lactam-ß-lactamase inhibitor combination with expanded antibacterial spectrum against Gram-negative pathogens including carbapenem-resistant Acinetobacter baumannii.
Antimicrob Agents Chemother;
68(3): e0112023, 2024 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38289044
2.
Designing Inhibitors of ß-Lactamase Enzymes to Overcome Carbapenem Resistance in Gram-Negative Bacteria.
Acc Chem Res;
54(9): 2055-2064, 2021 05 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33788541
3.
Novel Specific Metallo-ß-Lactamase Inhibitor ANT2681 Restores Meropenem Activity to Clinically Effective Levels against NDM-Positive Enterobacterales.
Antimicrob Agents Chemother;
65(6)2021 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33820763
4.
Pharmacodynamics of the Novel Metallo-ß-Lactamase Inhibitor ANT2681 in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae.
Antimicrob Agents Chemother;
64(11)2020 10 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32778549
5.
Discovery of a Novel Metallo-ß-Lactamase Inhibitor That Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacteriaceae.
Antimicrob Agents Chemother;
62(5)2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29530861
6.
Identifying public health policymakers' sources of information: comparing survey and network analyses.
Eur J Public Health;
27(suppl_2): 118-123, 2017 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26163470
7.
Reply to Asempa et al., "The Ongoing Challenge with NDM-Harboring Enterobacteriaceae in Murine Infection Models".
Antimicrob Agents Chemother;
65(2)2021 01 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-33229430
8.
Bridging, brokerage and betweenness.
Soc Networks;
44: 202-208, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-28239229
9.
Who runs public health? A mixed-methods study combining qualitative and network analyses.
J Public Health (Oxf);
35(3): 453-9, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23564840
10.
Higher levels of Pseudomonas aeruginosa LasB elastase expression are associated with early-stage infection in cystic fibrosis patients.
Sci Rep;
13(1): 14208, 2023 08 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37648735
11.
Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1ß in Cellular and Animal Infection Models.
ACS Infect Dis;
9(2): 270-282, 2023 02 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36669138
12.
Pseudomonas aeruginosa elastase (LasB) as a therapeutic target.
Drug Discov Today;
26(9): 2108-2123, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33676022
13.
Virtual Screening Approach to Identifying a Novel and Tractable Series of Pseudomonas aeruginosa Elastase Inhibitors.
ACS Med Chem Lett;
12(2): 217-227, 2021 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33603968
14.
Pseudomonas aeruginosa Elastase Contributes to the Establishment of Chronic Lung Colonization and Modulates the Immune Response in a Murine Model.
Front Microbiol;
11: 620819, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33510733
15.
Discovery of ANT3310, a Novel Broad-Spectrum Serine ß-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii.
J Med Chem;
63(24): 15802-15820, 2020 12 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-33306385
16.
ANT2681: SAR Studies Leading to the Identification of a Metallo-ß-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae.
ACS Infect Dis;
6(9): 2419-2430, 2020 09 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32786279
17.
SAR Studies Leading to the Identification of a Novel Series of Metallo-ß-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model.
ACS Infect Dis;
5(1): 131-140, 2019 01 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30427656
18.
Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement.
Lancet Infect Dis;
8(2): 133-9, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18222164
19.
Interaction of kendomycin and semi-synthetic analogues with the anti-apoptotic protein Bcl-xl.
Bioorg Med Chem Lett;
18(21): 5771-3, 2008 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18845435
20.
The Importance of External Contacts in Job Performance: A Study in Healthcare Organizations Using Social Network Analysis.
Int J Environ Res Public Health;
15(7)2018 06 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29954054